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白血病合并肺炎婴幼儿鼻咽抽吸物中肺孢子虫DNA的检测

Detection of pneumocystis DNA in nasopharyngeal aspirates of leukaemic infants with pneumonia.

作者信息

Richards C G, Wakefield A E, Mitchell C D

机构信息

John Radcliffe Hospital, Headington, Oxford.

出版信息

Arch Dis Child. 1994 Sep;71(3):254-5. doi: 10.1136/adc.71.3.254.

Abstract

The technique of polymerase chain reaction was used to detect Pneumocystis carinii DNA in nasopharyngeal secretions of three infants with leukaemia who had the clinical features of P carinii pneumonia. The use of this non-invasive technique allowed the early diagnosis and treatment of these infants whose protocols did not include the use of prophylactic co-trimoxazole.

摘要

采用聚合酶链反应技术检测了3例患有卡氏肺孢子虫肺炎临床特征的白血病婴儿鼻咽分泌物中的卡氏肺孢子虫DNA。这种非侵入性技术的应用使得这些未采用预防性复方新诺明治疗方案的婴儿得以早期诊断和治疗。

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