Aguilar J A, Summerson C, Flores D, Espinosa R A, Enciso R, Badui E, Hurtado R
División de Cardiología del Hospital de Especialidades, Centro Médico Nacional La Raza, IMSS.
Arch Inst Cardiol Mex. 1994 May-Jun;64(3):257-63.
In this study we evaluate prospectively a new color Doppler method for calculating the mitral valve area based on identifying a blue-red aliasing interfase proximal to the orifice, corresponding to the flow convergence region (FCR). This method can be used to calculate areas using the continuity equation. We studied 61 patients with stenosis. The mitral valve area was calculated using pressure half-time (PHT) Doppler method which were compared with values that obtained by the FCR method, according to the following formula. AVM (cm2) = 2 pi r2 x VN/Vmax; where "r" is the FCR radius measured from the orifice to the first color aliasing (blue-red interface); VN is Nyquist velocity and Vmax is the peak flow velocity by continuous wave Doppler. Twenty three patients had pure mitral stenosis and 38 double mitral lesion. Twenty patients were on sinus rhythm while 41 in atrial fibrillation. Calculated mitral valve area using the FCR method correlated well with mitral valve area determined by PHT method at a correlation coefficient of r = 0.96 (y = 0.097 x + 54.9, SEE = 0.10 cm2, p < 0.001). MVA by FCR ranged from 0.4 to 2.5 cm2 (mean = 1.19 cm2). MVA by PHT ranged from 0.42 to 2.48 cm2 (mean = 1.15 cm2). Color Doppler FCR method provides an accurate estimate of effective mitral valve area and may be useful as an alternative to the pressure half-time method. The calculated mitral valve area by the FCR method is not influenced by the presence of mitral regurgitation nor atrial fibrillation.
在本研究中，我们前瞻性地评估了一种新的彩色多普勒方法，该方法基于识别靠近瓣口的蓝红混叠界面（对应于血流会聚区，FCR）来计算二尖瓣面积。此方法可用于通过连续性方程计算面积。我们研究了61例狭窄患者。使用压力减半时间（PHT）多普勒方法计算二尖瓣面积，并根据以下公式将其与通过FCR方法获得的值进行比较。AVM（cm²）= 2πr²×VN/Vmax；其中“r”是从瓣口到第一个彩色混叠（蓝红界面）测量的FCR半径；VN是奈奎斯特速度，Vmax是连续波多普勒测得的峰值流速。23例患者为单纯二尖瓣狭窄，38例为二尖瓣双病变。20例患者为窦性心律，41例为心房颤动。使用FCR方法计算的二尖瓣面积与通过PHT方法确定的二尖瓣面积相关性良好，相关系数r = 0.96（y = 0.097x + 54.9，标准误SEE = 0.10 cm²，p < 0.001）。FCR法测得的二尖瓣面积范围为0.4至2.5 cm²（平均 = 1.19 cm²）。PHT法测得的二尖瓣面积范围为0.42至2.48 cm²（平均 = 1.15 cm²）。彩色多普勒FCR方法可准确估计二尖瓣有效面积，可作为压力减半时间方法的替代方法。FCR方法计算的二尖瓣面积不受二尖瓣反流和心房颤动的影响。
