Synthesis and hypotensive activity of some heterocyclic analogues of GYKI-12 743.
作者信息
Mátyus P, Kasztreiner E, Diesler E, Behr A, Varga I, Kosáry J, Rabloczky G, Jaszlits L
机构信息
Institute for Drug Research, Budapest, Hungary.
出版信息
Arch Pharm (Weinheim). 1994 Sep;327(9):543-6. doi: 10.1002/ardp.19943270902.
PMID:7979923
Abstract
[1,4]Benzodioxanylmethyl-, [1,4]benzodioxanylmethylaminopropyl- and phenoxyethylaminoethyl-substituted lactams were synthesised and their hypotensive activity was investigated. Some of these compounds show moderate to high hypotensive effect, but they had more toxic and/or side effects than GYKI-12 743.
摘要
Zotero 插件