Stepanov S A, Kirichenko A K, Aleskeev I A
Arkh Patol. 1993 Jan-Feb;55(1):64-8.
The role of chronic placental insufficiency in the ontogenetic maturation of fetal thyroid gland was studied in 75 cases. The second trimester of physiologically normal and complicated by premature delivery pregnancies showed correlations between organometric and histiostereometric indices of placenta and thyroid gland. In case of chronic placental insufficiency depression of placental metabolic processes was found associated with discoordination of histogenesis of fetal thyroid gland, a decrease of specific capacity of its parenchyma and vessels, as well as with growth of stroma component value. These prove reduced histiofunctional properties and adaptive reactions of placenta.
在75例病例中研究了慢性胎盘功能不全在胎儿甲状腺个体发育成熟中的作用。生理正常及合并早产的妊娠中期显示胎盘与甲状腺的器官测量和组织立体测量指标之间存在相关性。在慢性胎盘功能不全的情况下,发现胎盘代谢过程的抑制与胎儿甲状腺组织发生失调、其实质和血管的比容量降低以及间质成分值增加有关。这些证明了胎盘组织功能特性和适应性反应的降低。