Bridges R S
Department of Comparative Medicine, Tufts University School of Veterinary Medicine, North Grafton, Massachusetts 01536.
Acta Paediatr Suppl. 1994 Jun;397:33-9. doi: 10.1111/j.1651-2227.1994.tb13263.x.
Most mammals display an immediate onset of maternal care towards their offspring at parturition. In contrast, inexperienced, nulliparous females are often slow responders and show less intensity in their maternal responses. The transition from a slow responder in non-parous females to a rapid response at parturition is facilitated by the endocrine state of pregnancy. The present report reviews recent evidence from my laboratory demonstrating a role for prolactin in the stimulation of maternal behavior in the rat and presents new findings suggesting tht the conceptus, through its secretion of placental lactogens, helps prime the maternal brain (one site being the medial preoptic area) to respond maternally at parturition.
大多数哺乳动物在分娩时会立即对其后代表现出母性关怀。相比之下，没有经验的未生育雌性往往反应迟缓，且母性行为的强度较低。非生育雌性从反应迟缓到分娩时迅速做出反应的转变是由孕期的内分泌状态促成的。本报告回顾了我实验室最近的证据，这些证据证明催乳素在刺激大鼠母性行为中发挥作用，并呈现了新的研究结果，表明孕体通过分泌胎盘催乳素来帮助使母体大脑（其中一个部位是视前内侧区）做好准备，以便在分娩时做出母性行为反应。
