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血浆和尿液唾液酸在子宫颈癌中的诊断和预后作用

Diagnostic and prognostic role of plasma and urinary sialic acid in human carcinoma of uterine cervix.

作者信息

Balasubramaniyan N, Subramanian S, Sekar N, Bhuvarahamurthy V, Govindasamy S

机构信息

Department of Biochemistry, University of Madras, India.

出版信息

Biochem Mol Biol Int. 1994 Jul;33(4):617-23.

PMID:7981648
Abstract

In different stages of carcinoma of uterine cervix, the plasma total sialic acid (TSA), lipid bound sialic acid (LSA) and urinary sialic acid levels were studied before and after radiation treatment. Glycocomponents of glycoproteins were found to be increased progressively as the disease advances. The increased levels of glycocomponents were found to be decreased to near normal levels after radiotherapy. This may be a better indicator of the disease in conjunction with the studies of cervical smear rather than the latter alone.

摘要

在子宫颈癌的不同阶段,对放疗前后血浆总唾液酸(TSA)、脂质结合唾液酸(LSA)和尿唾液酸水平进行了研究。发现随着疾病进展,糖蛋白的糖成分逐渐增加。放疗后发现糖成分增加的水平降至接近正常水平。与宫颈涂片检查相比,这可能是该疾病更好的指标,而非仅依靠宫颈涂片检查。

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Diagnostic and prognostic role of plasma and urinary sialic acid in human carcinoma of uterine cervix.血浆和尿液唾液酸在子宫颈癌中的诊断和预后作用
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引用本文的文献

1
Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix.子宫颈癌中的血清糖缀合物与铜蓝蛋白
Indian J Clin Biochem. 2002 Jan;17(1):20-4. doi: 10.1007/BF02867936.
2
Increased expression of sialic acid in cervical biopsies with squamous intraepithelial lesions.鳞状上皮内病变宫颈活检中唾液酸表达增加。
Diagn Pathol. 2010 Nov 22;5:74. doi: 10.1186/1746-1596-5-74.