Medeira A, Dennis N, Donnai D
Regional Genetics Service, St Mary's Hospital, Manchester, UK.
Clin Dysmorphol. 1994 Jul;3(3):270-5. doi: 10.1097/00019605-199407000-00016.
We report three unrelated fetuses presenting with anencephaly, spinal dysraphism, cleft lip and palate and limb reduction defects. Review of the literature suggests that this association may be more commonly found than previously recognized and may indicate severe disturbance in early embryogenesis.
我们报告了三例互不相关的胎儿，他们患有无脑儿、脊柱裂、唇腭裂和肢体短小畸形。文献回顾表明，这种关联可能比之前认为的更为常见，且可能预示着早期胚胎发育过程中存在严重紊乱。
