高于常规剂量的氟哌啶醇：一项针对慢性精神分裂症患者的初步研究。
Higher than usual dosage of haloperidol: a pilot study in chronic schizophrenics.
作者信息
Pacquay M, Brasseur F
出版信息
Proc R Soc Med. 1976;69 suppl 1(Suppl 1):46-9. doi: 10.1177/00359157760690S112.
The effect of higher than usual dosages of haloperidol was studied in 38 chronic institutionalized schizophrenic patients for whom any hope of discharge had been abandoned. In 23 patients (61%) a marked or moderate improvement was observed. No striking differences were seen between patients simultaneously receiving or not receiving group therapy. The 15 remaining patients put on haloperidol alone showed some increase in psychomotor alertness, according to the nurses' judgement. It is clear from these results can be safely administered and can be of considerable value in chronic institutionalized schizophrenic patients.
对38名长期住院的精神分裂症患者研究了高于常规剂量的氟哌啶醇的效果，这些患者已放弃了出院的任何希望。在23名患者（61%）中观察到显著或中度改善。同时接受或未接受团体治疗的患者之间未发现明显差异。根据护士的判断，仅接受氟哌啶醇治疗的其余15名患者的精神运动警觉性有所提高。从这些结果可以清楚地看出，（氟哌啶醇）可以安全给药，并且对长期住院的精神分裂症患者具有相当大的价值。
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