高于常规剂量的氟哌啶醇：对“退缩型”精神分裂症患者的一项初步研究。
Higher than usual dosage of haloperidol: a pilot study in 'back ward' schizophrenics.
作者信息
Tanghe A, Declercq H
出版信息
Proc R Soc Med. 1976;69 suppl 1(Suppl 1):50-3. doi: 10.1177/00359157760690S113.
A study was carried out in 39 severe, chronic psychotic patients of the effect of rapidly increasing and larger than usual doses of haloperidol in bringing about an improvement in their condition. Symptoms clearly improved in 10 patients. No improvement was observed in the other 29. However, such a success rate with chemotherapy alone, achieved under conditions where occupational or group therapy could not be given, clearly demonstrates the value of such drug administration. Haloperidol has proved to be remarkably safe in this high dose regimen. It should certainly form an integral part of the more comprehensive therapy programmes of the future.
对39名重度慢性精神病患者进行了一项研究，旨在探讨快速增加并高于常规剂量的氟哌啶醇对改善其病情的效果。10名患者的症状明显改善。另外29名患者未观察到改善。然而，在无法进行职业治疗或集体治疗的情况下，仅通过化疗取得这样的成功率，清楚地证明了这种药物给药方式的价值。在这种高剂量方案中，氟哌啶醇已被证明非常安全。它肯定应成为未来更全面治疗方案的一个组成部分。
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