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Microbial sialidases: does bigger always mean better?

作者信息

Vimr E R

机构信息

Dept of Veterinary Pathobiology, University of Illinois, Urbana 61801.

出版信息

Trends Microbiol. 1994 Aug;2(8):271-7. doi: 10.1016/0966-842x(94)90003-5.

DOI:10.1016/0966-842x(94)90003-5
PMID:7981969
Abstract

Sialidases are a superfamily of N-acylneuraminate-releasing (sialic-acid-releasing) exoglycosidases found mainly in higher eukaryotes and in some, mostly pathogenic, viruses, bacteria and protozoans. The functions of sialidases are poorly understood and, until recently, their biochemical and evolutionary relationships were unclear. A comparative approach has demonstrated the remarkable similarities and differences between nonviral sialidases, and is providing clues about their functions.

摘要

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