del Rió Navarro B E, Briseño Pérez C, Sienra Monge J J, Prieto Urzúa L, Predes Novelo C, Carrillo H
Departamento de neumología y alergia, Hospital Infantil de México Federico Gómez.
Rev Alerg Mex. 1994 Jul-Aug;41(4):110-4.
Abnormalities in exchange and tendency to acidosis and hypoxemia are present in acute asthma. Oxygen arterial saturation (pulse oximetry) is a simple and useful method to evaluate oxygenation conditions. Pulse oximetry and spirometry before and after albuterol nebulization (150 mcg/kg/dose) were performed in 35 subjects. 7 to 14 years, with acute asthma, 68% were mild and the rest moderate. Oxygen saturation before nebulization was less than 90% in 30 children and increased in 27 of them (90%). Spirometry before nebulization showed FEV1 20% predictive values in 18 children and increased in 10 of them. Seven were hospitalized because of worse symptoms. 4 of them showed metabolic acidosis by the presence of lactate. We conclude that pulse oximetry is a useful and simple method for an objective evaluation of acute asthma and its complications, but it is not predictive for a therapeutic decision.
急性哮喘存在气体交换异常以及酸中毒和低氧血症倾向。动脉血氧饱和度（脉搏血氧饱和度测定）是评估氧合状况的一种简单且有用的方法。对35名7至14岁患有急性哮喘的受试者进行了沙丁胺醇雾化（150微克/千克/剂量）前后的脉搏血氧饱和度测定和肺活量测定。其中68%为轻度，其余为中度。雾化前30名儿童的血氧饱和度低于90%，其中27名（90%）有所升高。雾化前肺活量测定显示18名儿童的第一秒用力呼气量（FEV1）为预测值的20%，其中10名有所增加。7名因症状加重而住院。其中4名因存在乳酸而出现代谢性酸中毒。我们得出结论，脉搏血氧饱和度测定是客观评估急性哮喘及其并发症的一种有用且简单的方法，但它不能预测治疗决策。
