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评估鼻黏液纤毛清除功能作为强迫症患者鼻功能指标的研究:一项横断面研究。

Evaluation of Nasal Mucociliary Clearance as an Indicator of Nasal Function in Obsessive-Compulsive Patients: A Cross-Sectional Study.

作者信息

Koparal Mehtap, Kapici Yasar, Aslan Sefer, Hepkarsi Sevinc, Karataş Mehmet, Yılmazer Cüneyt

机构信息

Department of Otolaryngology, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey.

Kahta State Hospital Psychiatry Clinic, Adiyaman, Turkey.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):3263-3267. doi: 10.1007/s12070-023-03972-2. Epub 2023 Jun 19.

Abstract

UNLABELLED

This clinical study aimed to compare the mucociliary clearance time in patients with OCD, a disease associated with neural olfactory disorders, with a healthy control group. The mucociliary clearance time of fifty-one patients with OCD and fifty-two healthy patients (control group) was compared. The saccharin nasal mucociliary clearance test (NMCT) was applied and recorded the sociodemographic data of all participants. The NMCT was longer in OCD patients than healthy controls. There was no statistically significant difference in sociodemographic data between the groups. Our results show that olfactory transmission pathways may be affected in OCD patients.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s12070-023-03972-2.

摘要

未标注

本临床研究旨在比较强迫症患者(一种与神经嗅觉障碍相关的疾病)与健康对照组的黏液纤毛清除时间。比较了51名强迫症患者和52名健康患者(对照组)的黏液纤毛清除时间。应用糖精鼻黏液纤毛清除试验(NMCT)并记录了所有参与者的社会人口统计学数据。强迫症患者的NMCT比健康对照组更长。两组之间的社会人口统计学数据没有统计学上的显著差异。我们的结果表明,强迫症患者的嗅觉传导途径可能受到影响。

补充信息

在线版本包含可在10.1007/s12070-023-03972-2获取的补充材料。

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本文引用的文献

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Could the Thyroid Gland Dominate the Brain in Obsessive-Compulsive Disorder?甲状腺能在强迫症中主宰大脑吗?
Neuroendocrinology. 2022;112(12):1143-1154. doi: 10.1159/000524627. Epub 2022 Apr 20.
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Obsessive-Compulsive Disorder: Puzzles and Prospects.强迫症:谜题与展望。
Neuron. 2019 Apr 3;102(1):27-47. doi: 10.1016/j.neuron.2019.01.046.
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Mucociliary clearance: pathophysiological aspects.黏液纤毛清除功能:病理生理学方面
Clin Physiol Funct Imaging. 2014 May;34(3):171-7. doi: 10.1111/cpf.12085. Epub 2013 Sep 30.
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Brain structural imaging correlates of olfactory dysfunction in obsessive-compulsive disorder.强迫症中嗅觉功能障碍的脑结构成像相关性
Eur Arch Psychiatry Clin Neurosci. 2014 Apr;264(3):225-33. doi: 10.1007/s00406-013-0439-7. Epub 2013 Aug 31.
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