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绝经前期良性附件肿瘤的内镜手术治疗的安全性与有效性:一项前瞻性研究

[Safety and effectiveness of endosurgical management of benign adnexal tumors in the premenopausal period: a prospective study].

作者信息

Hesseling M, De Wilde R L

机构信息

Frauenklinik, Bethesda Krankenhaus, Wuppertal.

出版信息

Geburtshilfe Frauenheilkd. 1994 Aug;54(8):437-9. doi: 10.1055/s-2007-1022875.

Abstract

Between January 1985 and December 1989, a prospective laparoscopic study was performed in premenopausal women with pelvic cysts growing or persisting for at least three months or evoking acute abdominal complaints. The aim of this prospective study was the investigation of the functional/nonfunctional rate, the relapse and the malignancy rate. 372 women underwent a diagnostic-operative laparoscopy in the absence of irregular solid and cystic parts detectable by preoperative vaginal ultrasonography. The treatment consisted of non-randomised endosurgical ovarian cystostomy, cystectomy or ovarectomy. Histopathological assessment showed functional ovarian cysts in 268 women and non-functional benign ovarian tumours in 104. 2 cases were subsequently found to be malignant. After a mean follow-up-time of at least one year, we found an overall recurrence rate of 4.6% after cystostomy, 2% after cystectomy and 0% after ovarectomy in the group of functional ovarian cysts and a total of 1% after endosurgical therapy of the non-functional ovarian tumours. The diagnostic operative laparoscopy proved to be a safe and efficient treatment of pelvic cysts in women of reproductive age, provided a sufficient preoperative vaginal ultrasound examination had been performed.

摘要

1985年1月至1989年12月期间,对盆腔囊肿生长或持续至少三个月或引发急性腹部症状的绝经前女性进行了一项前瞻性腹腔镜研究。这项前瞻性研究的目的是调查功能性/非功能性比率、复发率和恶性率。372名女性在术前经阴道超声检查未发现不规则实性和囊性部分的情况下接受了诊断性手术腹腔镜检查。治疗方法包括非随机的内镜下卵巢囊肿造口术、囊肿切除术或卵巢切除术。组织病理学评估显示,268名女性为功能性卵巢囊肿,104名为非功能性良性卵巢肿瘤。随后发现2例为恶性。在平均至少一年的随访期后,我们发现功能性卵巢囊肿组中,囊肿造口术后总体复发率为4.6%,囊肿切除术后为2%,卵巢切除术后为0%;非功能性卵巢肿瘤经内镜治疗后总体复发率为1%。如果术前进行了充分的经阴道超声检查,诊断性手术腹腔镜检查被证明是治疗育龄期女性盆腔囊肿的一种安全有效的方法。

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