De Wilde R L, Hesseling M
Frauenklinik Pius Hospital, Oldenburg.
Geburtshilfe Frauenheilkd. 1994 Aug;54(8):440-3. doi: 10.1055/s-2007-1022876.
The management of postmenopausal adnexal tumours is still controversially discussed. Approximately 30% of all postmenopausal tumours are malignant. The standard operative approach for these adnexal masses is still the exploratory laparotomy although the advantages of laparoscopic procedure are obvious, even in older patients. The aim of this prospective study was to find out to what extent diagnostic-operative laparoscopy is able to replace laparotomy in the therapy of postmenopausal adnexal masses. From January 1990 to August 1992, 169 postmenopausal patients entered the prospective study. After careful preoperative diagnostics, 63 patients underwent a laparotomy (group B) and 106 patients a laparoscopy (group A). 10 of these 106 cases underwent laparotomy after diagnostic laparoscopy (group Ab). The main operative procedure in group Aa was laparoscopic adnexectomy after Semm. Mean operative time and mean postoperative hospital stay were significantly lower in patients, who only underwent laparoscopic operation (group Aa). One case (0.9%) of the laparoscopically operated patients was subsequently found to be malignant (histologic assessment) and immediately treated by laparotomy with hysterectomy and contralateral adnexectomy. The combination of vaginal examination, vaginal/abdominal ultrasonography (tumor marker CA 125) and a sufficient preoperative diagnostic during endosurgery (no proliferations on the ovary or peritoneal surface, no ascites) reduces the risk of operating a malignant tumour by laparoscopy to a minimum. We believe that operative laparoscopy of postmenopausal adnexal masses is a safe and efficient method in carefully selected women.
绝经后附件肿瘤的治疗仍存在争议。所有绝经后肿瘤中约30%为恶性。尽管腹腔镜手术的优势明显,即使对于老年患者也是如此,但这些附件包块的标准手术方法仍是剖腹探查术。这项前瞻性研究的目的是确定诊断性手术腹腔镜检查在绝经后附件包块治疗中能够在多大程度上替代剖腹探查术。从1990年1月至1992年8月,169例绝经后患者进入了这项前瞻性研究。经过仔细的术前诊断,63例患者接受了剖腹探查术(B组),106例患者接受了腹腔镜检查(A组)。这106例中的10例在诊断性腹腔镜检查后接受了剖腹探查术(Ab组)。Aa组的主要手术操作是Semm式腹腔镜附件切除术。仅接受腹腔镜手术的患者(Aa组)的平均手术时间和平均术后住院时间显著缩短。腹腔镜手术患者中有1例(0.9%)随后被发现为恶性(组织学评估),并立即通过剖腹探查术行子宫切除术和对侧附件切除术进行治疗。阴道检查、阴道/腹部超声检查(肿瘤标志物CA 125)以及在内镜手术期间进行充分的术前诊断(卵巢或腹膜表面无增生、无腹水)相结合,可将腹腔镜手术治疗恶性肿瘤的风险降至最低。我们认为,对于经过精心挑选的女性,绝经后附件包块的手术腹腔镜检查是一种安全有效的方法。