Godschalk M F, Chen J, Katz P G, Mulligan T
Division of Geriatrics, Medical College of Virginia, Richmond.
J Am Geriatr Soc. 1994 Dec;42(12):1263-5. doi: 10.1111/j.1532-5415.1994.tb06508.x.
To determine the efficacy of intracavernosal injection of prostaglandin E1 (alprostadil) in elderly men with erectile failure.
Prospective study.
Outpatients at a university-affiliated VA Medical Center.
Ten subjects aged 65 years and older with duration of erectile failure of 6 months or longer.
Subjects received intracavernosal injections of prostaglandin E1 in the office and self-administered intracavernosal prostaglandin E1 at home.
Penile rigidity was measured by palpation and by the Rigiscan rigidity monitor.
Intracavernosal injection of prostaglandin E1 produced erections adequate for intercourse in 9 of the 10 subjects. Attempts at intercourse were rated satisfactory by two-thirds of the subjects and their spouses.
Intracavernosal injection of prostaglandin E1 is safe and effective for erectile failure in elderly men.
确定海绵体内注射前列腺素E1（前列地尔）对老年勃起功能障碍男性的疗效。
前瞻性研究。
大学附属退伍军人医疗中心门诊。
10名年龄在65岁及以上、勃起功能障碍持续6个月或更长时间的受试者。
受试者在诊室接受海绵体内注射前列腺素E1，并在家自行进行海绵体内注射前列腺素E1。
通过触诊和阴茎硬度监测仪测量阴茎硬度。
10名受试者中有9名通过海绵体内注射前列腺素E1产生了足以进行性交的勃起。三分之二的受试者及其配偶对性交尝试的评价为满意。
海绵体内注射前列腺素E1对老年男性勃起功能障碍安全有效。
