Popov V I, Moisseeva A A, Zippel H P
Institute for Cell Biophysics, Russian Academy of Sciences, Pushchino.
J Hirnforsch. 1994;35(3):415-23.
Lamellar granules, 35 to 80 nm in diameter, are observed in the pia-arachnoid tissue of regenerated olfactory bulb and olfactory subtracts of the goldfish. The granules correspond to multiple stacks of disks which cover basal lamina of both pial and ependymal cell layers and blood vessels. The granules are also in close association with collagen fibril bundles. The granules are observed only in young goldfish or after bilateral olfactory tract transection in 1 year postoperated animals. Our findings suggest that these granules are secreted by connective tissue cells in response to damage associated with bilateral olfactory tract transection. Coexisting extracellular free granules and the granules covering basal lamina are simultaneously found in regenerated olfactory bulb and olfactory tract. Many of our findings, as far as we know, have not been described previously. The composition and function of these granules are at present unknown.
在再生嗅球的软脑膜-蛛网膜组织以及金鱼的嗅球切除部位观察到直径为35至80纳米的板层颗粒。这些颗粒对应于覆盖软膜和室管膜细胞层以及血管基底膜的多层盘状结构。这些颗粒还与胶原纤维束紧密相连。这些颗粒仅在幼龄金鱼或双侧嗅束横断术后1年的动物中观察到。我们的研究结果表明，这些颗粒是结缔组织细胞对双侧嗅束横断相关损伤作出反应而分泌的。在再生的嗅球和嗅束中同时发现了共存的细胞外游离颗粒和覆盖基底膜的颗粒。据我们所知，我们的许多发现以前尚未被描述过。这些颗粒的组成和功能目前尚不清楚。
