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金鱼嗅觉神经的快速再生:精细结构与行为

Fast regeneration of the olfactory nerve in goldfish: fine structure and behaviour.

作者信息

Hoyk Z, Lago-Schaaf T, Zippel H P, Füzesi G, Halász N

机构信息

Institute of Biophysics, Biological Research Centre, Hungarian Academy of Sciences, Szeged.

出版信息

J Hirnforsch. 1993;34(4):461-5.

PMID:8308261
Abstract

Normal olfaction-guided behaviour in goldfish returns surprisingly fast after bilateral transection of the olfactory nerve (ON). In order to find correlation between morphological changes and behaviour we performed parallel studies on the behaviour of the fish and the ultrastructure of the olfactory bulb in axotomised fish. Signs of degeneration were most prominent between the 4th and 6th day post-operatively. First appearance of regenerated ON fibres and terminals was noted on the 10th post-operative day. ON terminals became frequent again two weeks after the operation. This supports earlier suppositions that morphological regeneration plays a crucial role in the fast and complete restoration of olfaction-guided behaviour.

摘要

金鱼的嗅觉神经(ON)被双侧横断后,其正常的嗅觉引导行为恢复得惊人地快。为了找出形态变化与行为之间的相关性,我们对鱼的行为和嗅觉球在轴突切断鱼中的超微结构进行了平行研究。退化迹象在术后第4天至第6天最为明显。术后第10天注意到再生的ON纤维和终末首次出现。术后两周ON终末再次变得频繁。这支持了早期的推测,即形态再生在嗅觉引导行为的快速和完全恢复中起关键作用。

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