Graves T K, Schall W D, Refsal K, Nachreiner R F
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, East Lansing, MI 48824.
J Vet Intern Med. 1994 Jul-Aug;8(4):287-9. doi: 10.1111/j.1939-1676.1994.tb03234.x.
We measured plasma concentrations of cortisol and aldosterone before and after administration of adrenocorticotropin (ACTH) in dogs with trichuriasis. These dogs had physical examination, historical, and serum electrolyte findings suggestive of hypoadrenocorticism; trichuriasis-associated pseudohypoadrenocorticism has been reported previously. We found normal basal and ACTH-stimulated plasma cortisol concentrations. Basal and ACTH-stimulated plasma aldosterone concentrations were normal in 2 dogs and increased in 3 dogs, suggesting that the electrolyte abnormalities seen in this clinical syndrome are not due to aldosterone deficiency.
我们在感染鞭虫病的犬只中，测量了促肾上腺皮质激素（ACTH）给药前后的血浆皮质醇和醛固酮浓度。这些犬只的体格检查、病史及血清电解质检查结果提示存在肾上腺皮质功能减退；此前已有关于鞭虫病相关假性肾上腺皮质功能减退的报道。我们发现基础及ACTH刺激后的血浆皮质醇浓度正常。2只犬的基础及ACTH刺激后的血浆醛固酮浓度正常，3只犬的该浓度升高，这表明在这种临床综合征中所见的电解质异常并非由醛固酮缺乏所致。
