Bourne W M, McCarey B E, Kaufman H E
Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1976 Sep-Oct;81(5):743-53.
This paper presents a clinical specular microscope for the examination and photography of endothelial cells at high magnification (X200). The instrument is used easily during routine examination without inconvenience or discomfort to the patient. We have found the specular microscope extremely useful clinically in the elucidation and documentation of corneal endothelial diseases in vivo. This instrument allows the detection of endothelial damage or disease which may not be seen by slitlamp examination. The effects of normal aging, endothelial dystrophies, trauma, and inflammation can be monitored. The instrument is especially useful in the evaluation of ocular surgical procedures. It can be used on the first postoperative day without inconvenience to the patient or damage to the eye. By the comparison of photographs taken before and after the operation, an estimate of endothelial cell loss may be made. Thus, the endothelial effects of different techniques of cataract extraction intraocular lens insertion, and penetrating keratoplasty can be observed and compared. This new technique for the clinical examination of corneal diseases has great promise in improving diagnosis as well as therapy.
本文介绍了一种临床镜面显微镜，用于高倍（200倍）检查和拍摄内皮细胞。该仪器在常规检查中使用简便，不会给患者带来不便或不适。我们发现，该镜面显微镜在体内角膜内皮疾病的阐明和记录方面具有极高的临床应用价值。该仪器能够检测出裂隙灯检查可能无法发现的内皮损伤或疾病。可以监测正常衰老、内皮营养不良、创伤和炎症的影响。该仪器在眼科手术评估中特别有用。术后第一天即可使用，不会给患者带来不便，也不会损伤眼睛。通过比较手术前后拍摄的照片，可以估算内皮细胞的损失。因此，可以观察和比较白内障摘除、人工晶状体植入和穿透性角膜移植等不同技术对内皮的影响。这种角膜疾病临床检查的新技术在改善诊断和治疗方面具有广阔前景。
