Binkhorst C D, Loones L H, Nygaard P
Trans Ophthalmol Soc U K (1962). 1977 Apr;97(1):67-73.
The principle and technique of Maurice's method of microscopy of the corneal endothelium at high magnificant is discussed. An instrument is now available for clinical use (clinical specular microscope). The experience of the authors in patients with an intraocular lens is reported. A rather high deficit of endothelial cells was found in a series of 26 children and young adults, that had suffered injury from 2 to 11 years previously. An average immediate endothelial cell loss of only 6-7% was found in extracapsular cataract extraction with simultaneous implantation of a 2-loop or 4-loop intraocular lens. A striking difference was found between the two eyes of bilateral pseudophakic patients when one eye had undergone intracapsular surgery and the other eye extracapsular surgery. It had to be concluded that barrier deprivation of the intracapsular aphakic eye leads to continuing endothelial cell loss other than through ageing. Subclinical and clinical late corneal dystrophy therefore belong to the "barrier deprivation syndrome" together with retino-vascular accidents (macular and optic disc oedema) and vitreous degeneration.
讨论了莫里斯高倍角膜内皮显微镜检查法的原理和技术。现在有一种仪器可供临床使用（临床镜面显微镜）。报告了作者在人工晶状体患者中的经验。在一系列2至11年前受过损伤的26名儿童和年轻成年人中，发现内皮细胞有相当高的缺失。在囊外白内障摘除术同时植入双袢或四袢人工晶状体时，平均立即内皮细胞损失仅为6 - 7%。在双侧假晶状体患者中，当一只眼睛接受了囊内手术而另一只眼睛接受了囊外手术时，发现两只眼睛之间存在显著差异。必须得出结论，囊内无晶状体眼的屏障剥夺除了通过衰老外还会导致内皮细胞持续损失。因此，亚临床和临床晚期角膜营养不良与视网膜血管意外（黄斑和视盘水肿）以及玻璃体变性一起属于“屏障剥夺综合征”。
