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吡罗昔康引起肺部浸润和嗜酸性粒细胞增多。

Piroxicam induced pulmonary infiltrates and eosinophilia.

作者信息

Pfitzenmeyer P, Meier M, Zuck P, Peiffer G, Masson P, Turcu A, Piard F, Camus P

机构信息

Service de Gériatrie, Centre Hospitalier Régional et Universitaire de Dijon, France.

出版信息

J Rheumatol. 1994 Aug;21(8):1573-7.

PMID:7983669
Abstract

We describe 2 patients who developed pulmonary infiltrates while being treated with piroxicam. There was no satisfactory explanation other than drug induced lung disease for their illness. They had no exposure to pneumotoxic drugs or aerocontaminants. Microorganisms were not cultured in sputum or bronchoaveolar lavage. There was no underlying illness with possible lung involvement. Pulmonary infiltrates developed during piroxicam therapy, disappeared after drug withdrawal and recurred following rechallenge.

摘要

我们描述了2例在使用吡罗昔康治疗期间出现肺部浸润的患者。除药物性肺病外,对他们的病情没有其他令人满意的解释。他们没有接触过肺毒性药物或空气污染物。痰液或支气管肺泡灌洗中未培养出微生物。没有可能累及肺部的基础疾病。肺部浸润在吡罗昔康治疗期间出现,停药后消失,再次用药后复发。

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