Martins Rosane Rodrigues, Marchiori Edson, Viana Sérgio Lopes, Grillo Júnior Luiz Sérgio Pereira, Capelozzi Vera Luiza, Valença Laércio Moreira
Armed Forces Hospital - Brasília, Brazil.
J Bras Pneumol. 2008 Mar;34(3):181-4. doi: 10.1590/s1806-37132008000300009.
The authors report the case of a female patient who developed chronic eosinophilic pneumonia secondary to long-term use of nitrofurantoin for prophylaxis of recurrent urinary tract infections due to urethral stenosis. On high-resolution computed tomography scans, the pulmonary reaction to nitrofurantoin most commonly manifests as an interstitial-alveolar pattern in both lung bases. However, in this case, the alterations were most pronounced in the periphery of the upper lobes. In itself, this tomographic profile is strongly indicative of chronic eosinophilic pneumonia. The patient had previously been submitted to an open lung biopsy. The diagnosis of chronic eosinophilic pneumonia was confirmed through a review of the biopsy.
作者报告了一例女性患者的病例，该患者因尿道狭窄长期使用呋喃妥因预防复发性尿路感染而患上慢性嗜酸性粒细胞性肺炎。在高分辨率计算机断层扫描中，肺部对呋喃妥因的反应最常见的表现是双肺底部的间质-肺泡型。然而，在该病例中，改变在上叶周边最为明显。就其本身而言，这种断层扫描特征强烈提示慢性嗜酸性粒细胞性肺炎。该患者此前接受了开胸肺活检。通过对活检结果的复查，确诊为慢性嗜酸性粒细胞性肺炎。
