Kumanov Kh, Tsvetkov M
Khirurgiia (Sofiia). 1993;46(5):6-8.
Carcinoma of the prostate is a widespread disease posing serious problems, especially when patient in stage T3-T4 are concerned. Proceeding from clinical observations on 269 patients presenting the aforementioned condition, and on the basis of thorough clinical, laboratory and histologic studies, a combined therapeutic approach using cyproterone acetate is adopted, supplemented by orchiectomy in some patients, and transurethral resection in others. After 3-month treatment course, changes in the level of microelements, copper, zinc and iron in particular, are recorded. In some cases the level of prostate specific antigen is lowered. Control of the underlying disease is successfully attained in 72 per cent of the patients.
前列腺癌是一种广泛存在的疾病，会引发严重问题，尤其是对于处于T3 - T4期的患者。基于对269例患有上述病症患者的临床观察，并在全面的临床、实验室和组织学研究基础上，采用了醋酸环丙孕酮的联合治疗方法，部分患者辅以睾丸切除术，其他患者则进行经尿道切除术。经过3个月的治疗疗程后，记录了微量元素，特别是铜、锌和铁水平的变化。在某些情况下，前列腺特异性抗原水平降低。72%的患者成功实现了对基础疾病的控制。
