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[免疫学方法及其在肺结核治疗诊断中的应用]

[Immunologic methods and their use for diagnosis in the treatment of pulmonary tuberculosis].

作者信息

Knoring B E

出版信息

Probl Tuberk. 1994(4):25-7.

PMID:7984609
Abstract

The immunological survey of 1,688 patients with tuberculosis and 486 with non-specific pulmonary diseases was made. Criteria were identified for immunodiagnosis. The use of current mathematical methods of analysis allowed the development of high performance immunodiagnostic systems for pulmonary abnormalities, which included diagnostic tables and discriminant analysis by employing a computer. The major immunological disorders were determined, which in agreement with the definite direction of a tuberculous process with the subsequent use of data for monitoring the patient's status and correcting the treatment. The most potent immunocorrective drugs were studied, indications for their use were specified, proceeding from the immunological characterization of a specific patient. It was shown that the comprehensive assessment of various links of the immune system is of undoubtful value for the diagnosis and prediction of diseases, and prescription of immunocorrective therapy for pulmonary tuberculosis.

摘要

对1688例肺结核患者和486例非特异性肺部疾病患者进行了免疫学调查。确定了免疫诊断标准。采用当前的数学分析方法,开发出了用于肺部异常的高性能免疫诊断系统,其中包括诊断表以及使用计算机进行判别分析。确定了主要的免疫紊乱情况,这与结核病程的明确方向一致,随后利用这些数据监测患者状况并调整治疗方案。研究了最有效的免疫纠正药物,并根据特定患者的免疫学特征确定了其使用指征。结果表明,对免疫系统各个环节进行综合评估对于疾病的诊断、预测以及肺结核免疫纠正治疗的处方具有毋庸置疑的价值。

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