Stout R W
Acta Diabetol Lat. 1976 May-Aug;13(3-4):87-92. doi: 10.1007/BF02581251.
Arteries are not simply conduits for the transport of blood, but consist of metabolically active tissue which has the capacity to synthesize all the components of the atherosclerotic lesion. The smooth muscle cell appears to be the most important metabolically active cell in the arterial wall. There is little information on arterial metabolism in human diabetes. Experimental diabetes depressed all aspects of arterial lipid metabolism and this effect is reversed by insulin. Insulin promotes changes in arterial metabolism which are similar to those an atherosclerosis. Thus the relationship of human diabetes to the metabolism of the arterial wall is complex and little understood.
动脉并非仅仅是输送血液的管道，而是由具有代谢活性的组织构成，该组织有能力合成动脉粥样硬化病变的所有成分。平滑肌细胞似乎是动脉壁中最重要的代谢活跃细胞。关于人类糖尿病患者的动脉代谢情况所知甚少。实验性糖尿病会抑制动脉脂质代谢的各个方面，而这种作用可被胰岛素逆转。胰岛素会促进动脉代谢发生变化，这些变化与动脉粥样硬化时的变化相似。因此，人类糖尿病与动脉壁代谢之间的关系很复杂，人们对此了解甚少。
