Ferrer López J R, Sánchez Noda R, Perera de Puga G, Cong M Y, Sánchez Noda J
Instituto de Medicina Tropical Pedro Kourí, Laboratorio de Malacología.
Rev Cubana Med Trop. 1993;45(2):118-21.
A study was carried out on the molluscacidal action of agave (Agave legrelliana) on the mollusk Biomphalaria havanensis, host of Schistosoma. Different concentrations of the plant's juice extract were tested to determine lethal doses. 3 experimental series were carried out using 144 mollusks in each. LD50 = 0.14 mL/L and LD90 = 0.47 mL/L were determined using the "probilog" computerized program. The regression equation was Y = 5.29 + 2.53 in X. Density, pH, liquid content and absorbance of the juice were determined. The stability of the A. legrelliana juice extract was compared using LD90 and it was observed that its effectiveness was reduced after long storage periods. The results attained were very encouraging since large volumes of water abounding in intermediate host mollusks can be treated with small quantities of juice at the same time that the toxicity which might be introduced by products of chemical origin is reduced.
对龙舌兰（Agave legrelliana）对血吸虫中间宿主哈瓦那双脐螺（Biomphalaria havanensis）的杀螺作用进行了一项研究。测试了该植物汁液提取物的不同浓度以确定致死剂量。进行了3个实验系列，每个系列使用144只软体动物。使用“probilog”计算机程序确定LD50 = 0.14 mL/L和LD90 = 0.47 mL/L。回归方程为Y = 5.29 + 2.53 in X。测定了汁液的密度、pH值、液体含量和吸光度。使用LD90比较了龙舌兰汁液提取物的稳定性，观察到长时间储存后其有效性降低。所获得的结果非常令人鼓舞，因为大量中间宿主软体动物丰富的水体可以用少量汁液进行处理，同时减少了化学来源产品可能引入的毒性。
