Gómez J D, Malek E A, Vargas M
Rev Cubana Med Trop. 1989 May-Aug;41(2):236-41.
This paper reports the results of a preliminary study of the mollusk-killing properties of guayacil, a raw extract of the plant Guayacum officinalis, on Biomphalaria glabrata. Mollusks are exposed to several concentrations of the substance for periods ranging from 1, 6, and 24 hours and then were allowed to recover, according to the recommendations of the World Health Organization. The results indicate that guayacil has molusk-killing properties with an LC50 of 0.45 ppm and an LC90 of 0.95 ppm at 24 degrees C. Larger concentrations of 1 ppm resulted in 100% death rate, while 0.1 ppm did not prove lethal. All parts of the plant contain the active ingredient. Concentrations lower than 1 ppm are not lethal for flora or fauna.
本文报道了对植物愈创木（Guayacum officinalis）的粗提物愈创木脂对光滑双脐螺的杀螺特性进行的初步研究结果。根据世界卫生组织的建议，将软体动物暴露于该物质的几种浓度下1小时、6小时和24小时，然后使其恢复。结果表明，在24摄氏度时，愈创木脂具有杀螺特性，其半数致死浓度（LC50）为0.45 ppm，90%致死浓度（LC90）为0.95 ppm。浓度为1 ppm时导致100%死亡率，而0.1 ppm未证明具有致死性。该植物的所有部分都含有活性成分。低于1 ppm的浓度对动植物没有致死性。
