Mathieu E, Fain O, Trinchet J C, Aurousseau M H, Stérin D, Thomas M
Service de médecine interne, hôpital Jean-Verdier, Bondy, France.
Rev Med Interne. 1994;15(9):589-92. doi: 10.1016/s0248-8663(05)82504-4.
Among usual extra digestive manifestations of inflammatory bowel diseases, vascular injuries are rare, but often of excessive gravity. The emergence of a portal thrombosis, often accelerated by infection or traumatism, particularly surgical, remains exceptional. We report the case of a young patient who is followed for a severe crohn's disease and affected with a brutal portal vein thrombosis. Although initial prognosis was bad, the patient now lead a normal life ten months after this episode. It's the third described case of portal thrombosis in crohn's disease. We discuss the predisposing role of an acquired protein S deficiency during a estroprogestative treatment.
在炎症性肠病常见的消化道外表现中，血管损伤较为罕见，但往往较为严重。门静脉血栓形成的出现，通常由感染或创伤（尤其是手术创伤）加速，仍然较为罕见。我们报告了一名年轻患者的病例，该患者患有严重克罗恩病，并突然发生门静脉血栓形成。尽管初始预后不佳，但该患者在此次发作十个月后现在过着正常生活。这是克罗恩病中描述的第三例门静脉血栓形成病例。我们讨论了在雌孕激素治疗期间获得性蛋白S缺乏的 predisposing 作用。 （注：“predisposing”这里可能是“诱发、易患因素相关的”之类意思，原文这个词不太准确，结合语境猜测翻译）
