Giraud M J, Lemonnier E, Bigot T
Service de pédo-psychiatrie, hôpital international, Paris.
Rev Prat. 1994 Nov 1;44(17):2325-31.
Although the utility of psychotropic drugs has been well demonstrated, caution must still be exercised in their use. Among their potential risks, drug dependency must be kept in mind. This risk is well accepted with regard to benzodiazepines, and it appeared useful to study the potential risk for antidepressants, neuroleptics and thymoregulatory agents. Whatever the drug, the predominant factor appears to be psychological dependency. Prevention of drug dependency is most often achieved by informing the patient, limiting the length of use of the drug, making regular reevaluation of symptoms and of drug indication, and frequently be establishing a "treatment contract". The importance of the patient-physician relationship in the prescription of such treatment must be underlined.
尽管精神药物的效用已得到充分证明,但在使用时仍须谨慎。在其潜在风险中,必须牢记药物依赖问题。苯二氮䓬类药物的这种风险已被广泛认可,研究抗抑郁药、抗精神病药和胸腺调节药的潜在风险似乎很有必要。无论使用何种药物,主要因素似乎都是心理依赖。预防药物依赖通常通过告知患者、限制药物使用时长、定期重新评估症状和药物适应症以及频繁签订“治疗合同”来实现。必须强调医患关系在这类治疗处方中的重要性。