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原发性甲状旁腺功能亢进症手术失败的代价。

Cost of unsuccessful surgery for primary hyperparathyroidism.

作者信息

Doherty G M, Weber B, Norton J A

机构信息

Department of Surgery, Washington University School of Medicine, St. Louis, Mo.

出版信息

Surgery. 1994 Dec;116(6):954-7; discussion 957-8.

PMID:7985102
Abstract

BACKGROUND

Surgery for primary hyperparathyroidism demands skill and experience. The monetary and personal costs of unsuccessful surgery are investigated here.

METHODS

We reviewed 47 consecutive patients operated on by one surgeon during a period of 16 months, including their clinical data and medical costs of their treatment.

RESULTS

All 39 patients without previous operation were normocalcemic after operation, with no recurrent nerve injury nor hypoparathyroidism. Of the eight who had undergone previous operation elsewhere, seven had abnormal glands that should have been resected at the initial operation, and hypoparathyroidism developed in two patients. Total costs of reoperative parathyroid surgery were more than twice the cost of an initial operation (median, $8383 versus $3948, p < 0.001) because of the cost of radiologic studies (median, $3378 versus $43, p < 0.001).

CONCLUSIONS

(1) An experienced parathyroid surgeon can consistently cure hyperparathyroidism at the initial operation. (2) The majority of patients referred for hyperparathyroidism not cured by previous operation have glands in usual anatomic locations. (3) The cost to the patient of an inadequate initial operation includes the physical effects of remaining hyperparathyroid, additional time off work, potentially invasive localization testing, reoperative surgery with increased risk of complications, and substantial expense. Initial parathyroid surgery should be performed by surgeons experienced and proficient in its practice.

摘要

背景

原发性甲状旁腺功能亢进症的手术需要技巧和经验。本文对手术失败的金钱和个人代价进行了研究。

方法

我们回顾了一位外科医生在16个月期间连续为47例患者实施的手术,包括他们的临床资料和治疗的医疗费用。

结果

所有39例未曾接受过手术的患者术后血钙正常,无喉返神经损伤及甲状旁腺功能减退。在其他地方接受过手术的8例患者中,7例有本应在初次手术时切除的异常腺体,2例出现甲状旁腺功能减退。再次甲状旁腺手术的总费用是初次手术费用的两倍多(中位数分别为8383美元和3948美元,p<0.001),原因是放射学检查费用(中位数分别为3378美元和43美元,p<0.001)。

结论

(1)经验丰富的甲状旁腺外科医生能够在初次手术时持续治愈甲状旁腺功能亢进症。(2)大多数因先前手术未治愈而转诊的甲状旁腺功能亢进症患者的腺体位于正常解剖位置。(3)初次手术不充分给患者带来的代价包括甲状旁腺功能亢进持续存在的身体影响、额外的误工时间、可能具有侵入性的定位检查、并发症风险增加的再次手术以及高额费用。初次甲状旁腺手术应由经验丰富且精通该手术的外科医生进行。

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