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“福氏志贺菌”R突变体的化学型及相关噬菌体受体。I. —— 脂多糖的化学研究(作者译)

[Chemotypes of "Shigella flexneri" R mutants and related phage receptors. I. -- Chemical study of the lipopolysaccharides (author's transl)].

作者信息

Hannecart-Pokorni E, Godard C, Beumer J

出版信息

Ann Microbiol (Paris). 1976 Jul;127(1):3-14.

PMID:798513
Abstract

The F6R rough mutants isolated from Shigella flexneri F6S, serotype 5b, and the FH rough mutants, derived from other serotypes of S. flexneri, were chemotyped according to the chemical analysis of their lipopolysaccharides. Further, the following stages of lipopolysaccharide core biosynthesis in S. flexneri have been established: --(KDO)3--heptose--heptose--glucose--galactose; the last three stages are: either --glucose--glucosamine--glucose, or --glucosamine--glucose--glucose. The results of the chemical study of the R lipopolysaccharides are compatible with the assumption of the existence of a similar core in all considered S. flexneri serotypes.

摘要

从福氏志贺菌5b血清型F6S分离出的F6R粗糙突变体,以及源自福氏志贺菌其他血清型的FH粗糙突变体,根据其脂多糖的化学分析进行了化学分型。此外,已确定福氏志贺菌脂多糖核心生物合成的以下阶段:--(KDO)3--庚糖--庚糖--葡萄糖--半乳糖;最后三个阶段为:要么是--葡萄糖--葡糖胺--葡萄糖,要么是--葡糖胺--葡萄糖--葡萄糖。对R脂多糖的化学研究结果与所有所考虑的福氏志贺菌血清型中存在相似核心的假设相符。

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