Johansen C, Mellemgaard A, Skov T B, Kjaergaard J, Lynge E
Kraeftens Bekaempelse, sektor for kraeftepidemiologi, København.
Ugeskr Laeger. 1994 Oct 3;156(40):5840-3.
Nation-wide incidence rates are presented of colorectal cancer in Denmark from 1943 to 1988. In Denmark notification of malignant and related diseases is mandatory. The percentage of histologically confirmed tumours is now 95. The annual incidence rate of colon cancer in Denmark has been increasing among men and women combined from 684 cases in 1943-1947 to 2020 cases in 1988. In the same period the incidence of rectal cancer has increased from 762 cases in 1943-1947 to 1108 cases in 1988. We analyzed the effects of age, calender time, and birth cohort with multiplicative Poisson models. We did not find consistent period effects in the models. We suggest an etiologic distinction between carcinoma of the rectum, the left colon and the right colon.
本文呈现了1943年至1988年丹麦全国范围内的结直肠癌发病率。在丹麦，恶性及相关疾病的报告是强制性的。目前，组织学确诊肿瘤的比例为95%。丹麦结肠癌的年发病率在男性和女性中都有所上升，从1943 - 1947年的684例增加到1988年的2020例。同期，直肠癌的发病率从1943 - 1947年的762例增加到1988年的1108例。我们使用乘性泊松模型分析了年龄、日历时间和出生队列的影响。我们在模型中未发现一致的时期效应。我们建议对直肠癌、左半结肠癌和右半结肠癌进行病因学区分。
