猪链球菌1/2型链霉素依赖突变株的分离、特性鉴定及小鼠保护研究
Isolation, characterization and protection studies in mice of a streptomycin-dependent mutant of Streptococcus suis type 1/2.
作者信息
Foster N, Staats J J, Chengappa M M
机构信息
Department of Pathology and Microbiology, College of Veterinary Medicine, Kansas State University, Manhattan 66506.
出版信息
Vet Res Commun. 1994;18(3):155-63. doi: 10.1007/BF01839263.
PMID:7985376
Abstract
An avirulent, streptomycin-dependent (Str-D) mutant of Streptococcus suis type 1/2 was produced and characterized by its antimicrobial susceptibility, growth kinetics, biochemical reactions and reversion rate. Homologous and heterologous vaccine trials in mice resulted in complete protection against challenge with S. suis types 1 and 1/2 and partial protection against challenge with S. suis type 2.
摘要
制备了猪链球菌1/2型无毒、链霉素依赖（Str-D）突变株，并对其抗菌敏感性、生长动力学、生化反应和回复率进行了表征。在小鼠中进行的同源和异源疫苗试验对1型和1/2型猪链球菌攻击产生了完全保护，对2型猪链球菌攻击产生了部分保护。
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