Effects of concurrent oral administration of lead, selenium or monensin on hepatic porphyrin levels in broiler chickens during sub-acute toxicosis.

Liver-porphyrin levels were found to have increased during sub-acute lead toxicosis. The presence of selenium or monensin in the diet of lead-intoxicated birds resulted in a further increase of liver-porphyrin levels. The results of this study indicate the presence of an interaction between lead and selenium or monensin in producing an increase in porphyrins in the liver tissue of broiler chickens.