Vakhidov A, Muradov M K
Zh Vopr Neirokhir Im N N Burdenko. 1994 Jul-Sep(3):16-9.
To study abnormal external respiration function and pulmonary circulation in patients with severe brain injury, a total of 120 victims were examined. The static and dynamic parameters of external respiration function and pulmonary hemodynamics were determined every day within the first week and on days 10, 14, 21, and 28 of postinjury. The findings indicated that the causes of impaired external respiration function and circulation in brain injuries were decreases in lung volumes and capacities, disturbances in bronchial patency and alveolar ventilation uniformity followed by the development of lung and lung shunt atelectasis, changes in pulmonary circulation and elevations in pulmonary diastolic pressure, which depend upon the severity of an injury. At the same time it was found that patients with severe brain contusion developed bronchospasm, pulmonary hypertension with lesser pulmonary circulation twice more frequently than did those with moderate injuries.
为研究重型颅脑损伤患者的异常肺通气功能及肺循环情况,共对120例患者进行了检查。在伤后第一周内每天以及伤后第10、14、21和28天测定肺通气功能及肺血流动力学的静态和动态参数。结果表明,颅脑损伤时肺通气功能及循环障碍的原因是肺容积和容量减小、支气管通畅性及肺泡通气均匀性紊乱,随后出现肺不张和肺内分流,肺循环改变及肺舒张压升高,这些均取决于损伤的严重程度。同时还发现,重度脑挫裂伤患者发生支气管痉挛、肺动脉高压且肺循环较差的频率是中度损伤患者的两倍多。