Hetherington M M, Altemus M, Nelson M L, Bernat A S, Gold P W
Clinical Neuroendocrinology Branch, National Institute of Mental Health, NIH, Bethesda, MD.
Am J Clin Nutr. 1994 Dec;60(6):864-73. doi: 10.1093/ajcn/60.6.864.
Ten bulimic individuals were admitted to an inpatient unit and for 7 consecutive days eating behavior was observed and recorded. Age, sex, and weight-matched control subjects (n = 10) were admitted to the same unit for 4 d. All food and fluid intake, frequency of binge eating and purging, and ratings of appetite and mood before and after eating were recorded every 24 h. Bulimic patients demonstrated chaotic eating patterns that varied within as well as between individuals. Total daily energy intake was significantly higher for bulimic patients (41982 +/- 113 kJ; 10,034 +/- 2701 kcal) than for control subjects (8050 +/- 0427 kJ; 1924 +/- 102 kcal). On average, patients binged 1.6 times, purged three times, and ate one snack or meal without purging daily. Macronutrient analyses of intake revealed significantly less energy from protein and more energy from fat in bulimic patients compared with control subjects. Some improvement of mood was noted after binges, the magnitude of which was greatest after purging.
10名神经性贪食症患者被收治入院，连续7天对其饮食行为进行观察和记录。选取年龄、性别和体重匹配的对照受试者（n = 10），让他们在同一病房住院4天。每24小时记录所有食物和液体摄入量、暴饮暴食和催吐的频率，以及进食前后的食欲和情绪评分。神经性贪食症患者表现出混乱的饮食模式，个体内部和个体之间均存在差异。神经性贪食症患者的每日总能量摄入量（41982±113 kJ；10034±2701千卡）显著高于对照受试者（8050±427 kJ；1924±102千卡）。患者平均每天暴饮暴食1.6次，催吐3次，有一次小吃或正餐未进行催吐。对摄入量的宏量营养素分析显示，与对照受试者相比，神经性贪食症患者从蛋白质中获取的能量显著减少，从脂肪中获取的能量更多。暴饮暴食后情绪有一定改善，催吐后的改善程度最大。
