Wefel J S
Dows Institute for Dental Research, College of Dentistry, University of Iowa, Iowa City.
Am J Dent. 1994 Oct;7(5):261-5.
This paper reviews the histopathology of root surface caries, and the effect of fluoride on the root caries process. The root caries process may be defined as a dynamic equilibrium similar to enamel caries. The caries process produced acid demineralization in exposed root surfaces and resulted in a lesion body when viewed in the light microscope. A relatively intact surface layer was not always present unless root caries was observed. In the absence of fluoride, a significant surface layer was left devoid of mineral but with intact collagen. Fluoride helped to prevent lesion formation and produced radiodense banding within the lesions in in vitro models. Remineralization occurred on the remaining mineral and not on the collagen matrix devoid of mineral. The conversion of active to inactive root caries requires the formation of a mineralized layer and implies the loss of surface tissues and contour in the clinical situation.
本文综述了根面龋的组织病理学以及氟对根龋进程的影响。根龋进程可定义为一种类似于釉质龋的动态平衡。龋病进程在暴露的根面产生酸脱矿，在光学显微镜下观察时会形成病变体。除非观察到根龋，否则相对完整的表层并不总是存在。在无氟的情况下，会留下一个明显的表层，其矿物质缺失但胶原完整。在体外模型中，氟有助于预防病变形成并在病变内产生放射致密带。再矿化发生在剩余的矿物质上，而不是在无矿物质的胶原基质上。活跃性根龋转变为静止性根龋需要形成矿化层，这意味着在临床情况下会出现表面组织和外形的丧失。
