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Review of investigative diagnostic techniques for cutaneous lymphoma.

作者信息

Slater D N

机构信息

Department of Histopathology, Rotherham Hospital NHS Trust, United Kingdom.

出版信息

Semin Dermatol. 1994 Sep;13(3):166-71.

PMID:7986684
Abstract

This article reviews the contribution of modern investigative techniques to the diagnosis of cutaneous lymphoproliferative diseases. Special attention is given to the significance of immunoglobulin and T-cell receptor rearrangements; as detected by Southern blotting and/or the polymerase chain reaction. Additional topics discussed include immunohistochemistry, cytogenetics, onco- and tumour suppressor genes and in-situ hybridization. It is recommended that the results of these techniques are interpreted in the form of a multifaceted diagnostic profile.

摘要

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