1983年意大利国民健康调查中的饮酒情况与自我报告的胆结石疾病患病率

Alcohol drinking and prevalence of self-reported gallstone disease in the 1983 Italian National Health Survey.

作者信息

La Vecchia C, Decarli A, Ferraroni M, Negri E

机构信息

Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.

出版信息

Epidemiology. 1994 Sep;5(5):533-6.

PMID:7986868

Abstract

We studied the relation between alcohol drinking and gallstone disease, using data from the 1983 Italian National Health Survey. This survey included information on 58,462 adults age 25 years and over (27,912 males and 30,550 females), randomly selected within strata of geographical area, size of the municipality of residence, and size of the household. The prevalence of gallstone disease or cholecystectomy was 2.4% among males and 4.8% among females. Compared with alcohol abstainers, the relative risk of gallstone disease, controlling for age, sex, education, smoking, and body mass index, was 0.83 [95% confidence interval (CI) = 0.73-0.92] for occasional and regular moderate drinkers (< 25 ml of ethanol per day), 0.67 (95% CI = 0.59-0.77) for intermediate drinkers (25-50 ml per day), and 0.58 (95% CI = 0.47-0.70) for heavy drinkers. This inverse association was consistent across strata of age, sex, and body mass index.

摘要

我们利用1983年意大利全国健康调查的数据，研究了饮酒与胆结石疾病之间的关系。这项调查涵盖了年龄在25岁及以上的58462名成年人（27912名男性和30550名女性），这些人是在地理区域、居住城市规模和家庭规模等分层中随机选取的。男性胆结石疾病或胆囊切除术的患病率为2.4%，女性为4.8%。与戒酒者相比，在控制年龄、性别、教育程度、吸烟情况和体重指数后，偶尔和经常适度饮酒者（每天乙醇摄入量<25毫升）患胆结石疾病的相对风险为0.83[95%置信区间（CI）=0.73 - 0.92]，中度饮酒者（每天25 - 50毫升）为0.67（95%CI = 0.59 - 0.77），重度饮酒者为0.58（95%CI = 0.47 - 0.70）。这种负相关在年龄、性别和体重指数分层中均一致。