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长期使用苯丙胺者用药途径的转变。

Transitions between routes of administration of regular amphetamine users.

作者信息

Darke S, Cohen J, Ross J, Hando J, Hall W

机构信息

National Drug and Alcohol Research Centre, University of New South Wales, Australia.

出版信息

Addiction. 1994 Sep;89(9):1077-83. doi: 10.1111/j.1360-0443.1994.tb02784.x.

DOI:10.1111/j.1360-0443.1994.tb02784.x
PMID:7987184
Abstract

A sample of 301 regular amphetamine users was interviewed regarding transitions between routes of administration of amphetamines. Use of amphetamines by injecting was widespread, with two-thirds (67%) of subjects having injected the drug during the preceding 6 months. Needle-sharing was common, with 41% of injectors having shared a needle in the month preceding interview. A transition to regular amphetamine injecting from other routes of administration was reported by 40% of subjects, with males being twice as likely to report such a transition. The median number of such transitions was one. The main reasons given by subjects for the transition to injecting were liking the "rush" from injecting, and seeing it as a more economical and a healthier way to use. A small proportion of subjects (9%) reported a transition away from injecting amphetamines, with a median of one such transition. The most common reason given for abandoning injecting was concern about vascular damage. Interventions to encourage safer use of amphetamines need to address the misconceptions that injecting is more economical and more healthy, and to emphasize the vascular problems associated with injecting.

摘要

对301名常规使用苯丙胺的使用者进行了关于苯丙胺给药途径转变的访谈。注射使用苯丙胺的情况很普遍,三分之二(67%)的研究对象在过去6个月内曾注射过该药物。共用针头的现象很常见,41%的注射者在访谈前一个月曾共用过针头。40%的研究对象报告了从其他给药途径转变为常规注射苯丙胺的情况,男性报告这种转变的可能性是女性的两倍。这种转变的中位数次数为1次。研究对象给出的转变为注射的主要原因是喜欢注射带来的“快感”,并认为这是一种更经济、更健康的使用方式。一小部分研究对象(9%)报告了从注射苯丙胺转变为其他方式的情况,这种转变的中位数次数为1次。放弃注射的最常见原因是担心血管损伤。鼓励更安全使用苯丙胺的干预措施需要解决关于注射更经济、更健康的误解,并强调与注射相关的血管问题。

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