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以耳声发射检测随后进行听性脑干反应作为听力障碍通用新生儿筛查测试的可行性。

Feasibility of otoacoustic emission detection followed by ABR as a universal neonatal screening test for hearing impairment.

作者信息

Hunter M F, Kimm L, Cafarlli Dees D, Kennedy C R, Thornton A R

机构信息

Department of Child Health, Southampton General Hospital, UK.

出版信息

Br J Audiol. 1994 Feb;28(1):47-51. doi: 10.3109/03005369409077912.

Abstract

The feasibility of attempting a two-stage universal screening test for auditory impairment was assessed at a large district maternity hospital. The first stage was measurement of otoacoustic emissions using the Programmable Otoacoustic Emission Measurement System. Those failing the first stage proceeded to automated analysis of auditory brainsteam responses. A single tester working for 6 h on 6 days per week attempted to test all babies born between the hours of midday and midnight for 2 weeks and then all babies born between midnight and midday for a further 2 weeks. Of 217 babies born during the study periods, one infant died and three were still receiving intensive care at the end of the study. Of the remaining 213 infants, auditory testing was undertaken in 201 infants (94%). Eight infants (4%) who failed the first stage of the screening test did not undergo the second stage. Of those 193 infants completing the screen, one (0.5%) failed the screen unilaterally. There were no bilateral failures. Three testers, working two and a half whole-time equivalents, should be adequate to achieve a coverage of 90% and a specificity of 99% for this screen in this clinical setting.

摘要

在一家大型地区妇产医院评估了尝试进行两阶段听力障碍通用筛查测试的可行性。第一阶段是使用可编程耳声发射测量系统测量耳声发射。第一阶段测试未通过的婴儿进入听觉脑干反应的自动分析。一名测试人员每周工作6天,每天工作6小时,试图对中午至午夜出生的所有婴儿进行为期2周的测试,然后对午夜至中午出生的所有婴儿再进行为期2周的测试。在研究期间出生的217名婴儿中,1名婴儿死亡,3名婴儿在研究结束时仍在接受重症监护。在其余213名婴儿中,201名婴儿(94%)接受了听力测试。8名(4%)第一阶段筛查测试未通过的婴儿未进行第二阶段测试。在完成筛查的193名婴儿中,1名(0.5%)单侧筛查未通过。没有双侧未通过的情况。在这种临床环境下,三名测试人员(相当于两个半全时工作量)应足以使该筛查的覆盖率达到90%,特异性达到99%。

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