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新生儿听力筛查中自动听性脑干反应的敏感性。

Sensitivity of the Automated Auditory Brainstem Response in Neonatal Hearing Screening.

出版信息

Pediatrics. 2015 Sep;136(3):e641-7. doi: 10.1542/peds.2014-3784.

Abstract

BACKGROUND

In a 2-stage neonatal hearing screening protocol, if an infant fails the first-stage abstract screening with an otoacoustic emissions test, an automated auditory brainstem response (ABR)test is performed. The purpose of this study was to estimate the rate of hearing loss detected byfirst-stage otoacoustic emissions test but missed by second-stage automated ABR testing.

METHODS

The data of 17 078 infants who were born at Lis Maternity Hospital between January 2013 and June 2014 were reviewed. Infants who failed screening with a transient evoked otoacoustic emissions (TEOAE) test and infants admitted to the NICU for more than 5 days underwent screening with an automated ABR test at 45 decibel hearing level (dB HL). All infants who failed screening with TEOAE were referred to a follow-up evaluation at the hearing clinic.

RESULTS

Twenty-four percent of the infants who failed the TEOAE and passed the automated ABR hearing screening tests were eventually diagnosed with hearing loss by diagnostic ABR testing (22/90). They comprised 52% of all of the infants in the birth cohort who were diagnosed with permanent or persistent hearing loss .25 dB HL in 1 or both ears (22/42).Hearing loss .45 dB HL, which is considered to be in the range of moderate to profound severity, was diagnosed in 36% of the infants in this group (8/22), comprising 42% of the infants with hearing loss of this degree (8/19).

CONCLUSIONS

The sensitivity of the diverse response detection methods of automated ABR devices needs to be further empirically evaluated.

摘要

背景

在两阶段新生儿听力筛查方案中,如果婴儿在使用耳声发射测试的第一阶段抽象筛查中未通过,将进行自动听性脑干反应(ABR)测试。本研究的目的是估计第一阶段耳声发射测试检测到但第二阶段自动 ABR 测试未检测到的听力损失率。

方法

回顾了 2013 年 1 月至 2014 年 6 月期间在利斯妇产医院出生的 17078 名婴儿的数据。未能通过瞬态诱发耳声发射(TEOAE)测试筛查的婴儿和因入住 NICU 超过 5 天而未能通过自动 ABR 测试筛查的婴儿,在 45 分贝听力水平(dB HL)下进行 ABR 测试。所有未能通过 TEOAE 筛查的婴儿均被转介至听力诊所进行随访评估。

结果

24%的 TEOAE 测试未通过但通过自动 ABR 听力筛查测试的婴儿最终通过诊断性 ABR 测试被诊断为听力损失(22/90)。他们占整个出生队列中所有被诊断为永久性或持续性听力损失的婴儿的 52%(22/42)。在该组婴儿中,36%(8/22)被诊断为听力损失.45 dB HL,这被认为属于中度至重度听力损失范围,占该程度听力损失婴儿的 42%(8/19)。

结论

需要进一步通过经验评估自动 ABR 设备的各种反应检测方法的灵敏度。

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