CYP3A酶的非侵入性检测 - Suppr | 超能文献

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Noninvasive tests of CYP3A enzymes.CYP3A酶的非侵入性检测

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2

Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol.代谢红霉素和皮质醇的细胞色素P450 3A亚型的异质性

Clin Pharmacol Ther. 1992 Jan;51(1):18-23. doi: 10.1038/clpt.1992.3.

3

Concurrent administration of the erythromycin breath test (EBT) and oral midazolam as in vivo probes for CYP3A activity.将红霉素呼气试验（EBT）与口服咪达唑仑同时作为CYP3A活性的体内探针使用。

J Clin Pharmacol. 1999 Dec;39(12):1212-20. doi: 10.1177/00912709922012015.

4

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test.

Drug Metab Dispos. 1994 Nov-Dec;22(6):947-55.

5

Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men.年轻健康男性体内三种假定的细胞色素P4503A活性探针之间不存在相关性。

Clin Pharmacol Ther. 1993 Dec;54(6):621-9. doi: 10.1038/clpt.1993.199.

6

Early postoperative erythromycin breath test correlates with hepatic cytochrome P4503A activity in liver transplant recipients.肝移植受者术后早期红霉素呼气试验与肝细胞色素P4503A活性相关。

Clin Pharmacol Ther. 2001 Nov;70(5):446-54.

7

Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine.

Clin Pharmacol Ther. 1996 Jan;59(1):47-51. doi: 10.1016/S0009-9236(96)90023-5.

8

Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes.使用细胞色素P450 3A4表型探针预测伊立替康的药代动力学

J Natl Cancer Inst. 2004 Nov 3;96(21):1585-92. doi: 10.1093/jnci/djh298.

9

Effect of age and gender on the activity of human hepatic CYP3A.

Biochem Pharmacol. 1992 Jul 22;44(2):275-83. doi: 10.1016/0006-2952(92)90010-g.

10

Importance of cytochrome P-450IIIA activity in determining dosage and blood levels of FK 506 and cyclosporine in liver transplant recipients.细胞色素P-450IIIA活性在确定肝移植受者中FK 506和环孢素剂量及血药浓度方面的重要性。

Hepatology. 1994 Aug;20(2):309-16.

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Roles of Individual Human Cytochrome P450 Enzymes in Drug Metabolism.个体人类细胞色素 P450 酶在药物代谢中的作用。

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Exploring the multiple effects of nifedipine and captopril administration in spontaneously hypertensive rats through pharmacokinetic-pharmacodynamic analyses.通过药代动力学-药效学分析探索硝苯地平和卡托普利对自发性高血压大鼠的多种作用。

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Formation of CYP3A-specific metabolites of ibrutinib in vitro is correlated with hepatic CYP3A activity and 4β-hydroxycholesterol/cholesterol ratio.