Vallée L, Pinton F, Martin B H, Debray P, Vamecq J, Hladky J P, Nuyts J P
Service des maladies infectieuses et de neurologie infantiles, hôpital B, CHRU, Lille, France.
Arch Pediatr. 1994 Feb;1(2):166-9.
Brain abscess following dental or periapical infection is rare in childhood. This report describes brain abscesses found in two children with dental caries. Case 1.--A 12 year-old boy was admitted because he had suffered from acute meningitis for 3 days. Clinical examination showed symptoms of meningitis plus palsy of the right third and fourth cranial nerves and of the left facial nerve, and a defect in the left temporal field. Funduscopic examination showed papilledema; CT scan and MRI showed a ring-shaped lesion in the right occipital area. The patient was given cefotaxime and thiamphenicol. The abscess was drained; bacteriological examination showed Actinomyces viscosus and Peptostreptococcus magnus. The neurological condition and the CT scan lesion improved, but intracranial pressure increased again on the 17th day after the onset, requiring replacement of the antibiotics by rifampicin and ampicillin plus clavulanic acid for 2 months. This brain abscess appeared to be metastatic, derived from the infection of a large dental cyst due to a dental infection that had been treated 6 months earlier. Case 2.--A 8 1/2 year-old girl was admitted because she was suffering from palsy of the left facial nerve and left arm. She had had headaches and fever for a few days. Clinical examination showed the palsies and drowsiness. CT scan showed two brain abscesses. The patient was given ceftriaxone, fosfocin and metronidazole. She had been treated for a gingival abscess 1 month earlier, and had two infected teeth extracted. Improvement of the intracranial pressure was transient and the antibiotics were changed on the 12th day of treatment.(ABSTRACT TRUNCATED AT 250 WORDS)
儿童期因牙源性或根尖周感染导致的脑脓肿较为罕见。本报告描述了两名患有龋齿的儿童所发生的脑脓肿。病例1:一名12岁男孩因患急性脑膜炎3天入院。临床检查显示有脑膜炎症状,伴有右侧第三和第四颅神经及左侧面神经麻痹,左侧颞叶视野缺损。眼底检查显示视乳头水肿;CT扫描和MRI显示右侧枕叶区有一个环形病变。给予患者头孢噻肟和甲砜霉素治疗。脓肿进行了引流;细菌学检查显示有粘性放线菌和巨大消化链球菌。神经状况和CT扫描病变有所改善,但发病后第17天颅内压再次升高,需要将抗生素换成利福平以及氨苄西林加克拉维酸,持续治疗2个月。这个脑脓肿似乎是转移性的,源于6个月前因牙科感染治疗的一个大型牙囊肿的感染。病例2:一名8岁半女孩因左侧面神经和左臂麻痹入院。她已经头痛和发热了几天。临床检查显示有麻痹和嗜睡症状。CT扫描显示有两个脑脓肿。给予患者头孢曲松、磷霉素和甲硝唑治疗。她1个月前曾因牙龈脓肿接受治疗,并且拔除了两颗感染的牙齿。颅内压的改善是短暂的,治疗第12天更换了抗生素。(摘要截选至250字)