Ponder B A
CRC Human Cancer Genetics Research Group, Department of Pathology, Cambridge, UK.
Br Med Bull. 1994 Jul;50(3):732-45. doi: 10.1093/oxfordjournals.bmb.a072921.
This article is based on the author's own experience of establishing and running a familial cancer clinic over the past 9 years. There are certainly other ways of doing it, depending on the clinical context--resources, involvement of colleagues from other specialities--and each clinic should be adapted to local circumstances. As the familial component of the common cancers such as breast and colorectal cancers is increasingly recognised, and DNA-based predictive testing becomes a possibility, the future demand for genetic advice is likely to increase dramatically. This will almost certainly require a re-appraisal of the way in which familial cancer services are provided, which is discussed in the final section.
本文基于作者在过去9年中建立和运营一家家族性癌症诊所的亲身经历。当然，根据临床情况——资源、其他专科同事的参与情况——还有其他的做法，每个诊所都应因地制宜。随着乳腺癌和结直肠癌等常见癌症的家族性成分越来越受到认可，基于DNA的预测性检测成为可能，未来对基因咨询的需求可能会大幅增加。几乎可以肯定，这将需要重新评估提供家族性癌症服务的方式，这将在最后一部分进行讨论。
