Raabo E, Odum L
Department of Clinical Chemistry, Holbaek Central Hospital, Denmark.
Clin Chem. 1994 Dec;40(12):2223-6.
Desktop analyzers and single-test meters used in primary healthcare are mainly calibrated to measure whole blood. To minimize matrix effects of control materials in external quality assessment schemes, we stabilized fresh human EDTA-treated blood with sodium iodoacetate (1.8 mmol/L). The whole-blood based control material was useful for control of hemoglobin and glucose, the two most common analyses in primary care, even after storage at room temperature for at least 10 days and at 5 degrees C for 3 weeks. The material was also useful for control of cholesterol and creatinine analyses for samples stored as long as 3 days at ambient temperature.
基层医疗保健中使用的台式分析仪和单测试血糖仪主要校准用于测量全血。为了在外部质量评估计划中尽量减少对照材料的基质效应，我们用碘乙酸钠（1.8 mmol/L）稳定新鲜的人乙二胺四乙酸（EDTA）处理血。这种基于全血的对照材料对于基层医疗中最常见的两项分析——血红蛋白和葡萄糖的质量控制很有用，即使在室温下储存至少10天以及在5摄氏度下储存3周后仍是如此。该材料对于在环境温度下储存长达3天的样本的胆固醇和肌酐分析的质量控制也很有用。
