人类RAD51/RecA同源基因不是布卢姆综合征的候选基因。
The human RAD51/RecA homologue gene is not a candidate gene for Bloom's syndrome.
作者信息
Hellgren D, Sahlén S, Ljungqvist S, Kenne K
机构信息
Unit for Environmental Medicine, Karolinska Institute, NOVUM, Huddinge, Sweden.
出版信息
Hum Genet. 1994 Dec;94(6):705-7. doi: 10.1007/BF00206968.
PMID:7989048
Abstract
The human gene HSRAD51/RecA homologue has been investigated as a possible candidate gene involved in Bloom's syndrome. No mutations were found in the cDNA isolated from three different Bloom's syndrome cell lines, thus excluding the possibility that HSRAD51 is directly involved in the syndrome. Other possible candidates are discussed.
摘要
人类基因HSRAD51/RecA同源物已作为参与布卢姆综合征的一个可能候选基因进行了研究。在从三种不同的布卢姆综合征细胞系中分离出的cDNA中未发现突变，因此排除了HSRAD51直接参与该综合征的可能性。文中讨论了其他可能的候选基因。
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