Barley J, Blackwood A, Sagnella G, Markandu N, MacGregor G, Carter N
Medical Genetics Unit, St. George's Hospital Medical School, London, UK.
J Hum Hypertens. 1994 Aug;8(8):639-40.
We describe angiotensinogen gene (AGT) polymorphic frequencies in different ethnic groups in London, both normotensive and hypertensive. The methodology is a recently described direct PCR technique. Results show that there is a marked difference in T-235 frequency between ethnic groups. However, there was no apparent association of T-235 with hypertension.
我们描述了伦敦不同种族(包括血压正常者和高血压患者)中血管紧张素原基因(AGT)的多态性频率。所采用的方法是一种最近描述的直接PCR技术。结果显示,不同种族之间T-235频率存在显著差异。然而,T-235与高血压之间没有明显关联。