4-Deacetyltaxol and 10-acetyl-4-deacetyltaxotere: synthesis and biological evaluation.
作者信息
Datta A, Jayasinghe L R, Georg G I
机构信息
Department of Medicinal Chemistry, University of Kansas, Lawrence 66045.
出版信息
J Med Chem. 1994 Nov 25;37(24):4258-60. doi: 10.1021/jm00050a023.
PMID:7990125
Abstract
4-Deacetyltaxol and 10-acetyl-4-deacetyltaxotere were synthesized for the first time from 7-(triethylsilyl)-4-deacetylbaccatin III. These analogs were found to be inactive in the microtubule assembly assay.
摘要
Zotero 插件