Tynecka M
Katedry i Kliniki Neurologii AM, Lublinie.
Neurol Neurochir Pol. 1994 Jul-Aug;28(4):515-22.
The purpose of this study was to determine the ferrokinetics in patients suffering from acute cerebral vascular diseases by assaying the iron and transferrin levels in the blood serum. Studies were performed on 80 patients. Also a single estimation of the haemoglobin level and of the red blood cell counts were performed in each patient. The iron level in the blood serum was assayed by photocolorimetry, while the level of transferrin was tested by radial immunodiffusion technique. The obtained results were analysed statistically by t-Student test. The accepted significance level was p < 0.05. In all groups of stroke patients a decrease of the average iron level and increase of the average transferrin level in the blood serum was found. It can be explained by the general disorders of the metabolism during the course of acute cerebral vascular disorders and feed-back mechanism.
本研究的目的是通过检测血清中铁和转铁蛋白水平来确定急性脑血管疾病患者的铁动力学。对80例患者进行了研究。同时对每位患者进行了血红蛋白水平和红细胞计数的单次测定。血清中铁水平采用光电比色法测定,转铁蛋白水平采用放射免疫扩散技术检测。所得结果采用t检验进行统计学分析。接受的显著性水平为p < 0.05。在所有中风患者组中,均发现血清中铁平均水平降低,转铁蛋白平均水平升高。这可以用急性脑血管疾病过程中代谢的普遍紊乱和反馈机制来解释。